2. Hydrogen Peroxide was used and recommended in federal decontamination responses to the anthrax bioterrorism attacks of
October 2001.

3. October 2005 Journal of Applied Microbiology, volume 99, issue 4, pages 739–748: “In aqueous or gaseous forms, hydrogen
peroxide exhibits decontamination efficacy against bacterial spores, vegetative bacteria, viruses, amoeba, and prions.
Hydrogen peroxide is considered less toxic than other fumigants such as chlorine dioxide, ethylene oxide, and
formaldehyde, and breaks down into water and oxygen. Therefore, hydrogen peroxide has been used as a decontaminant for
treating laboratory and medical equipment, pharmaceutical facilities, hospital rooms, and animal holding rooms.”

4. Some quaternary ammonium compounds are inactivated in the presence of some soaps or soap residues, so careful product
selection is important. Their antibacterial activity is reduced in the presence of organic material. Quaternary
ammoniums are cationic detergents; however, most are inactivated by contact with soaps or soap residues.

5. Disinfectants based on quaternary ammonium compounds (QAC) are frequently used in both medical environments and food
industries. There is general consensus that the wide-spread use and misuse of QAC have imposed a strong selective
pressure and contributed to the emergence of disinfectant resistance microorganisms in these environments.
Resistance to Quaternary Ammonium Compounds in Food-Related Bacteria
Maan Singh Sidhu, Henning Sørum, Askild Holck
Microbial Drug Resistance. Dec 2002, Vol. 8, No. 4: 393-399
Abstract | Full Text PDF | Reprints & Permissions
Genetic Linkage Between Resistance to Quaternary Ammonium Compounds and β-Lactam Antibiotics in Food-Related
Staphylococcus spp.

Maan Singh Sidhu, Even Heir, Henning Sørum, Askild Holck \
Microbial Drug Resistance. Dec 2001, Vol. 7, No. 4: 363-371

6. The standard soaps and detergents (without the added antibacterials), alcohol, hydrogen peroxide, are fully capable of
reducing the potential problematic pathogens and those should be preferred.

Technology – Antibiotic Resistance Atul K. Verma, Ph.D.
10/24/2005

7. Microbial drug resistance is a growing problem. The rise in multiresistant strains of bacteria observed over recent
decades emphasizes the importance of the development of new, innovative, antimicrobial drugs. There is a great deal of
interest in naturally occurring antimicrobial products, and intensive research aimed at the development of drugs based
on naturally occurring antimicrobial peptides (AMPs) of various origins is being performed.1–3 Despite such efforts
over the past 2 decades, clinical success has been limited.4 Other naturally occurring antimicrobial products with
clinical potential are enzymes, which produce antimicrobial products. Hydrogen peroxide (H2O2) is such a potent
antimicrobial product of enzyme activity that killing microorganisms through the oxidation of biologically important
molecules readily diffuses across cell membranes.